Endocrine Abstracts

Background Fibrocystic osteitis is rare PHPT manifestation. Poor management and delay in diagnosis of fibrocystic osteitis may lead to reduced quality of life and also provoke severe postoperative hypocalcemia – «hungry bone» syndrome.Clinical case We present a case of 66-years-old Caucasian woman, with history of urulithiasis/nephrocalcinosis (CKD stage 4), two pathological fractures, and fibrocystic osteitis. In Jan 2021...

Purpose: D631Y is a rare mutation associated with MEN2a in which there is an aspartic acid to tyrosine amino acid substitution at codon 631 in exon 11. Common clinical features of this variant of RET mutation are pheochromocytoma in 50%, medullary carcinoma in 30%, primary hyperparathyroidism is very rare. We present the patient harboring RET D631Y mutation.Clinical case: In April 2017 40-year-old woman was admitted to endocrine department of the Almazov...